Dimitrakopoulos, Panagiotis (Panos)

Associate Professor

Chemical and Biomolecular Engineering
Maryland Energy Innovation Institute

1227B Chemical and Nuclear Engineering Building

dimitrak@umd.edu

301-405-8166

Website(s):
Homepage

EDUCATION

Ph.D., University of Illinois at Urbana-Champaign, 1998

Postdoc, California Institute of Technology, 2001

PROFESSIONAL MEMBERSHIPS

American Institute of Chemical Engineers
The Society of Rheology
American Physical Society
Technical Chamber of Greece

BIOGRAPHY

Dr. Dimitrakopoulos is the director of the BioFluid Dynamics Computational Laboratory in the Department of Chemical and Biomolecular Engineering at the University of Maryland. His group's research involves the dynamics of droplets, capsules and erythrocytes in microfluidics, the microcirculation and porous media, hemodynamics and hemopathology in the microcirculation, the dynamics of synthetic and biological polymers as well as the development of novel computational methodologies for the accurate and efficient study of these physical systems.

Dimitrakopoulos' research has resulted in publications in the Journal of Fluid Mechanics, Physics of Fluids, Journal of Computational Physics, Journal of Chemical Physics, Physical Review E, Physical Review Letters, Soft Matter and the Biophysical Journal. His group's work has been supported by grants from the National Science Foundation (NSF), the National Institutes of Health (NIH), the ACS Petroleum Research Fund, and Supercomputing Facilities from the Extreme Science and Engineering Discovery Environment (XSEDE) which is supported by the National Science Foundation.

Dr. Dimitrakopoulos received his Diploma degree in chemical engineering from the National Technical University of Athens (NTUA), Greece, and his M.S. and Ph.D. degrees in chemical engineering (with option in computational science and engineering) from the University of Illinois at Urbana-Champaign (UIUC). He completed his postdoctoral study in the Department of Chemical Engineering at California Institute of Technology (Caltech).

Computational fluid dynamics
Dynamics of droplets, capsules and erythrocytes in microfluidics, the microcirculation and porous media
Hemodynamics and hemopathology in the microcirculation
Dynamics of synthetic and biological polymers
Numerical analysis

For a detailed list of current research projects, please visit www.eng.umd.edu/~dimitrak/pd-current-research.html.

Professor Dimitrakopoulos current teaches or has taught the following courses:

CHBE 250: Computer Methods in Chemical Engineering
CHBE 422: Chemical and Biomolecular Engineering Transport Phenomena I
CHBE 481/ENCH 648W: Transport Phenomena in Small and Biological Systems
ENCH620: Methods of Engineering Analysis
ENCH630: Transport Phenomena

Biofluid Dynamics: Flow in Microfluidics

Dimitrakopoulos, P. 2017 "Dumbbell formation for elastic capsules in nonlinear extensional Stokes flows'' Phys. Rev. Fluids, 2, 063101.
Koolivand A. and Dimitrakopoulos P. 2017 "Deformation of an elastic capsule in a microfluidic T-junction: settling shape and moduli determination" Microfluidics and Nanofluidics, 21, 89.
Boruah N. and Dimitrakopoulos P. 2015 "Motion and deformation of a droplet in a microfluidic cross-junction" J. Colloid Interface Sci., 453 216-225.
Dimitrakopoulos P. and Kuriakose S. 2015 "Determining a membrane's shear modulus, independent of its area-dilatation modulus, via capsule flow in a converging micro-capillary" Soft Matter, 11, 2782-2793.
K. Jiang, A. X. Lu, P. Dimitrakopoulos, S. R. Raghavan and D. L. DeVoe 2015 "Microfluidic generation of uniform water droplets using gas as the continuous phase" J. Colloid Interface Sci., 448, 275-279.
Dodson W. R. III and Dimitrakopoulos, P. 2014 "Properties of the spindle-to-cusp transition in extensional capsule dynamics" Europhys. Lett., 106, 48003.
Dimitrakopoulos, P. 2014 "Effects of membrane hardness and scaling analysis for capsules in planar extensional flows" J. Fluid Mech., 745, 487-508.
Park Sun-Young and Dimitrakopoulos, P. 2013 "Transient dynamics of an elastic capsule in a microfluidic constriction" Soft Matter, 9, 8844-8855.
Kuriakose S. and Dimitrakopoulos, P. 2013 "Deformation of an elastic capsule in a rectangular microfluidic channel" Soft Matter, 9, 4284-4296.
Dimitrakopoulos, P., 2012 "Analysis of the variation in the determination of the shear modulus of the erythrocyte membrane: Effects of the constitutive law and membrane modeling" Phys. Rev. E, 85, 041917.
Dodson W. R. III and Dimitrakopoulos, P., 2012 "Tank-treading of swollen erythrocytes in shear flows" Phys. Rev. E, 85, 021922.
Dimitrakopoulos, P., 2011 "Comment on "Tank-treading and tumbling frequencies of capsules and red blood cells" Phys. Rev. E, 84, 058301.
Dodson W. R. III and Dimitrakopoulos, P., 2011 "Oscillatory tank-treading motion of erythrocytes in shear flows" Phys. Rev. E, 84, 011913.
Kuriakose S. and Dimitrakopoulos, P., 2011 "Motion of an elastic capsule in a square microfluidic channel" Phys. Rev. E, 84, 011906.
Dodson W. R. III and Dimitrakopoulos, P., 2010 "Tank-treading of erythrocytes in strong shear flows via a non-stiff cytoskeleton-based continuum computational modeling" Biophys. J., 99, 2906-2916.
Dodson W. R. III and Dimitrakopoulos, P., 2009 "Dynamics of strain-hardening and strain-softening capsules in strong planar extensional flows via an interfacial spectral boundary element algorithm for elastic membranes" J. Fluid Mech., 641, 263-296.
Takemura F., Magnaudet J. and Dimitrakopoulos, P., 2009 "Migration and deformation of bubbles rising in a wall-bounded shear flow at finite Reynolds number" J. Fluid Mech., 634, 463-486.
Dodson W. R. III and Dimitrakopoulos, P., 2008 "Spindles, cusps and bifurcation for capsules in Stokes flow" Phys. Rev. Lett., 101, 208102.
Wang Yechun and Dimitrakopoulos, P., 2006 "A three-dimensional spectral boundary element algorithm for interfacial dynamics in Stokes flow" Phys. Fluids, 18, 082106(1-16).
Wang Yechun and Dimitrakopoulos, P., 2006 "Nature of the hemodynamic forces exerted on vascular endothelial cells or leukocytes adhering to the surface of blood vessels" Phys. Fluids, 18, 087107(1-14).
Wang Yechun and Dimitrakopoulos, P., 2006 "Normal force exerted on vascular endothelial cells" Phys. Rev. Lett., 96, 028106.

Dynamics of Multiphase Flows: Flow in Porous Media

Wang Yechun and Dimitrakopoulos, P., 2012 "Low-Reynolds-number droplet motion in a square microfluidic channel" Theor. Comput. Fluid Dyn., 26, 361-379.
Dimitrakopoulos, P., 2007 "Gravitational effects on the deformation of a droplet adhering to a horizontal solid surface in shear flow" Phys. Fluids, 19, 122105(1-14).
Dimitrakopoulos, P., 2007 "Deformation of a droplet adhering to a solid surface in shear flow: onset of interfacial sliding" J. Fluid Mech., 580, 451-466.
Dimitrakopoulos, P. and Higdon, J.J.L., 2003 "On the displacement of fluid bridges from solid surfaces in viscous pressure-driven flows" Phys. Fluids, 15 (10), 3255-3258.
Dimitrakopoulos, P. and Higdon, J.J.L., 2001 "On the displacement of three-dimensional fluid droplets adhering to a plane wall in viscous pressure-driven flows" J. Fluid Mech., 435, 327-350.
Dimitrakopoulos, P. and Higdon, J.J.L., 1999 "On the gravitational displacement of three-dimensional fluid droplets from inclined solid surfaces" J. Fluid Mech., 395, 181-209.
Dimitrakopoulos, P. and Higdon, J.J.L., 1998 "On the displacement of three-dimensional fluid droplets from solid surfaces in low-Reynolds-number shear flows" J. Fluid Mech., 377, 189-222.
Dimitrakopoulos, P. and Higdon, J.J.L., 1997 "Displacement of fluid droplets from solid surfaces in low-Reynolds-number shear flows" J. Fluid Mech., 336, 351-378.
Dimitrakopoulos, P., 2003 "Conformational evolution of initially straight flexible and stiff polymers over extended time periods via the scaling law methodology " J. Chem. Phys., 119 (15), 8189-8196.
Dimitrakopoulos, P., 2004 "Longitudinal relaxation of initially straight flexible and stiff polymers" Phys. Rev. Lett., 93, 217801.

Biophysics and Microrheology: Dilute Solutions of Biopolymers

Dissanayake, I. D. and Dimitrakopoulos, P., 2006 "Stress, birefringence and conformational relaxation of an initially straight stiff bead-rod polymer" Phys. Rev. E, 74, 021918(1-14).
Dimitrakopoulos, P., 2004 "Stress and configuration relaxation of an initially straight flexible polymer" J. Fluid Mech., 513, 265-286.
Dimitrakopoulos, P., 2004 "Longitudinal relaxation of initially straight flexible and stiff polymers" Phys. Rev. Lett., 93, 217801.
Dimitrakopoulos, P., 2003 "Conformational evolution of initially straight flexible and stiff polymers over extended time periods via the scaling law methodology " J. Chem. Phys., 119 (15), 8189-8196.
Dimitrakopoulos, P., Brady, J. F. and Wang, Zhen-Gang, 2001 "Short- and intermediate-time behavior of the linear stress relaxation in semiflexible polymers" Phys. Rev. E., 64 (5), 050803(R).

Numerical Analysis: Development of Efficient Computational Methodologies

Dimitrakopoulos, P., 2017 "Spectral Boundary Element Algorithms for Multi-Length Interfacial Dynamics" (pages 43-52), Book Chapter in "Integral Methods in Science and Engineering, Volume 2: Practical Applications", Editors: Christian Constanda, Matteo Dalla Riva, Pier Domenico Lamberti, Paolo Musolino
Dodson W. R. III and Dimitrakopoulos, P., 2010 "Tank-treading of erythrocytes in strong shear flows via a non-stiff cytoskeleton-based continuum computational modeling" Biophys. J., 99, 2906-2916.
Wang Yechun and Dimitrakopoulos, P., 2010 "Computational studies of interfacial dynamics in microfluidics via a 3D spectral boundary integral algorithm" In Proceedings of the ASME 2009 2nd Micro/Nanoscale Heat and Mass Transfer International Conference, December 18-21, 2009, Shanghai, China, MNHMT2009, 3, 659-662.
Dodson W. R. III and Dimitrakopoulos, P., 2009 "Dynamics of strain-hardening and strain-softening capsules in strong planar extensional flows via an interfacial spectral boundary element algorithm for elastic membranes" J. Fluid Mech., 641, 263-296.
Dimitrakopoulos, P., 2007 "Interfacial dynamics in Stokes flow via a three-dimensional fully-implicit interfacial spectral boundary element algorithm" J. Comp. Phys., 225, 408-426.
Dimitrakopoulos, P., and Wang Jingtao, 2007 "A spectral boundary element algorithm for interfacial dynamics in two-dimensional Stokes flow based on Hermitian interfacial smoothing" Eng. Anal. Bound. Elem., 31, 646-656.
Wang Yechun and Dimitrakopoulos, P., 2006 "A three-dimensional spectral boundary element algorithm for interfacial dynamics in Stokes flow" Phys. Fluids, 18, 082106(1-16).
Wang Yechun, Dodson W. R. III and Dimitrakopoulos, P., 2006 "Dynamics of multiphase flows via spectral boundary elements and parallel computations" In Parallel Computational Fluid Dynamics: Theory and Applications, A. Deane, G. Brenner, A. Ecer, D. Emerson, J. McDonough, J. Periaux, N. Satofuka and D. Tromeur-Dervout (Eds.). Elsevier/North-Holland, 405-412.
Dissanayake I. D. and Dimitrakopoulos, P. 2006 "Dynamics of biological and synthetic polymers through large-scale parallel computations" In Parallel Computational Fluid Dynamics: Theory and Applications, A. Deane, G. Brenner, A. Ecer, D. Emerson, J. McDonough, J. Periaux, N. Satofuka and D. Tromeur-Dervout (Eds.). Elsevier/North-Holland, 211-218.
Dimitrakopoulos, P. 2003 "Conformational evolution of initially straight flexible and stiff polymers over extended time periods via the scaling law methodology " J. Chem. Phys., 119 (15), 8189-8196.
Dimitrakopoulos, P. and Higdon, J.J.L., 1998 "On the displacement of three-dimensional fluid droplets from solid surfaces in low-Reynolds-number shear flows" J. Fluid Mech., 377, 189-222.
Dimitrakopoulos, P. and Higdon, J.J.L., 1997 "Displacement of fluid droplets from solid surfaces in low-Reynolds-number shear flows" J. Fluid Mech., 336, 351-378.

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