Event
ChBE Seminar Series: Osvaldo Gutierrez, UMD
Tuesday, November 28, 2017
11:00 a.m.
2108, Chemical and Nuclear Engineering Building
Dongxia Liu
liud@umd.edu
Speaker: Osvaldo Gutierrez, Assistant Professor of Chemistry, UMD
Title: Mechanism-Driven Engineering of Iron Catalysts for Asymmetric C(sp3)-X Functionalization
Abstract:
The development of selective catalyst-controlled functionalization of alkyl halides and aliphatic C-H bonds (C(sp3)-X functionalization) is one of the grand challenges in organic synthesis. Realization of this goal will open the door to the development of new chiral centers and enable cost-effective methods to quickly increase molecular complexity en route to biologically active compounds, natural products, and pharmaceutical agents. In this talk, I will discuss recent progress in bridging computation and experiment to accelerate engineering of catalysts for selective iron-catalyzed C(sp3)-X functionalization reactions.
