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MSE Seminar - Prof. Antonios Zavaliangos, Drexel University
Friday, October 3, 2008
1:00 p.m.
Rm. 2108, Chemical and Nuclear Engineering Bldg.
For More Information:
Annette Mateus
301 405 5207

“Pharmaceutical Powder Compaction: Numerical Simulations and Characterization Experiments”

The compaction of powders into solid parts is a common step in manufacturing in a diverse range of industries. Understanding the processing conditions and their implication on the properties of the compacts has been the focus of intense research recently.

In this presentation the following topics will be discussed:

(a) experimental calibration of constitutive models of powder compaction using a minimal set of experiments.

(b) implementation of predictive compaction models in commercial finite element software. This tool allows for predictions of compaction load, density variation within the compact, and a glimpse to post compaction properties. Validation studies and extension of this framework to roll compaction will be discussed.

(c) advanced numerical studies of multiparticle level simulations that model the compact at the particle level have employed to understand compact strength and anisotropy.

(d) modern characterization techniques such as x-ray microtomography applied to pharmaceutical powder compaction.

This Event is For: Public

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